The most current recommendations by the AAFP regarding FISS: *Sited from the 2013 AAFP Feline Vaccination Guidelines*
1) Recommend/administer vaccines on the basis of reasonable risk for exposure to the infectious pathogen to avoid unnecessary vaccination of cats
2) Studies have suggested that the risk of FISS increases as the number of vaccines received over time increases
3) Administer vaccines only as frequently as needed to provide protective immunity to avoid unnecessary vaccination of cats
4) Administer FPV, FHV-1, FCV no more often than every 3 years, except in high-risk situations
5) Administer parenteral feline vaccines by the SC route only to facilitate early detection of tumor. Vaccine administered by the IM route does not reduce the risk of tumorigenesis and may delay the detection of a mass located within muscle (vs skin). It is recommended that all parenteral vaccines be administered by the SC route
6) Use recommended vaccination sites (*whenever possible) to facilitate complete tumor removal......in the event that FISS develops
7) Consider vaccine type to reduce the risk of chronic local inflammation at the injection site, which may occur in some cats
8) The role of adjuvants (including those containing aluminum) and local inflammation in the pathogenesis of FISS is not clear. Both
adjuvanted and non-adjuvanted vaccines induce local inflammation, although the magnitude and type of inflammation varies among vaccines, adjuvants and individual cats. However, some authors recommend considering non-adjuvanted vaccines to try to reduce local inflammation
1) Recommend/administer vaccines on the basis of reasonable risk for exposure to the infectious pathogen to avoid unnecessary vaccination of cats
2) Studies have suggested that the risk of FISS increases as the number of vaccines received over time increases
3) Administer vaccines only as frequently as needed to provide protective immunity to avoid unnecessary vaccination of cats
4) Administer FPV, FHV-1, FCV no more often than every 3 years, except in high-risk situations
5) Administer parenteral feline vaccines by the SC route only to facilitate early detection of tumor. Vaccine administered by the IM route does not reduce the risk of tumorigenesis and may delay the detection of a mass located within muscle (vs skin). It is recommended that all parenteral vaccines be administered by the SC route
6) Use recommended vaccination sites (*whenever possible) to facilitate complete tumor removal......in the event that FISS develops
7) Consider vaccine type to reduce the risk of chronic local inflammation at the injection site, which may occur in some cats
8) The role of adjuvants (including those containing aluminum) and local inflammation in the pathogenesis of FISS is not clear. Both
adjuvanted and non-adjuvanted vaccines induce local inflammation, although the magnitude and type of inflammation varies among vaccines, adjuvants and individual cats. However, some authors recommend considering non-adjuvanted vaccines to try to reduce local inflammation